Shoujo Yuugi(2002)

Shoujo Yuugi

Luticia is a vampire. However, she has fallen in love with her childhood friend, a human named Shou. She is afraid that their love will not be able to overcome their differences. Rick, a vampire from Luticia’s Clan, is murdered by a woman from Shou’s village. Regardless, the vampire clan starts planning to revenge the murder of their own kind. Humans are also enraged to discover thee existence of vampires in the vicinity and they are also planning to find and destroy the vampires.

(from Animenewsnetwork)